Otolaryngology Resident’s Research on MMA Honored

By Dirk Hoffman

Published June 10, 2025

Sofia Khan, DO.

Sofia Khan, DO

Sofia Khan, DO, a first-year trainee in the at the , has been recognized for her research that resulted in a first-author publication in the British Journal of Oral and Maxillofacial Surgery.

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Her , titled “Outcomes of Maxillomandibular Advancement (MMA) by Dentofacial Class: A Systematic Review and Meta-Analysis,” was published in the peer-reviewed journal in February.

Khan’s research was subsequently honored with a first-place award in the 2025 research paper competition of the American Osteopathic Colleges of Ophthalmology and Otolaryngology — Head and Neck Surgery (AOCOO-HNS).

Reviewing An Effective Surgical Option for OSA

Khan notes that obstructive sleep apnea (OSA) is a highly prevalent condition with significant health risks.

She says the research study investigated how advancing both the upper and lower jaw influences sleep outcomes in individuals with different bite types — namely, Class I (normal bite), Class II (overbite) and Class III (underbite).

“Our research demonstrates that maxillomandibular advancement is an effective surgical option for OSA, regardless of the bite type,” she says. “With a better understanding of surgery outcomes, physicians can expect better sleep, lower risk of heart disease and improved quality of life in patients undergoing MMA.”

Khan says having any paper published as the first author is an incredibly rewarding experience.

“It often takes months — sometimes even years — from the initial idea to final publication, with the collaborative efforts of physicians, statisticians, and medical students,” she says. “Seeing that work published in a journal such as the British Journal of Oral and Maxillofacial Surgery brings a deep sense of accomplishment and validation.”

Khan presented her prize-winning research at the 2025 AOCOO-HNS annual clinical assembly April 30-May 2 in New Orleans.

“It’s always very exciting to be able to share your novel findings with an audience,” she says. “I hope that my research inspired students to always ask questions and be skeptical — perhaps they can find the answer to their own question!”

UB Residency Interview Felt Very Welcoming

Khan grew up in Morton Grove, Illinois, a suburb of Chicago, and received her doctor of osteopathic medicine degree from the Chicago College of Osteopathic Medicine.

Between her third and fourth years of medical school, Khan also completed a research year at the Medical ÃÛÌÒ´«Ã½ of South Carolina.

“It was during this time, under the guidance of Shaun Nguyen, MD, that I learned how to conduct research projects, including the project that led to my published paper on MMA,” she says.

Khan says she chose the ÃÛÌÒ´«Ã½ for her otolaryngology residency training because she immediately felt a strong connection with the residents during her interview.

“It genuinely felt like a place I could call home,” she says.

And due to the high surgical volume at the Erie County Medical Center — the region’s Level I Trauma Center — Khan was assured that she would graduate “with the operative experience and skills needed to become a competent surgeon.”

“Additionally, the program’s strong emphasis on research aligns with my own passion for research and allows me to continue contributing to evidence-based medicine throughout my training,” she says.